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Benacerraf was born in 1949 in New York City. She was the daughter of Baruj Benacerraf, who shared the 1980 Nobel Prize in Physiology or Medicine. She spent her early years in France and returned to New York City at age seven, attending the Brearley School and Barnard College in Manhattan. Although undiagnosed dyslexia had impaired her academic performance as an undergraduate, Benacerraf stated it was less of a handicap in medical school, where the textbooks included "a lot of graphs an

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